Boost Your Cardiovascular Health
Cardiovascular disease (CVD), which includes disorders of the heart and blood vessels, is the number 1 cause of death globally.
That’s the bad news.
Here’s the good news: CVD is mostly preventable! Your lifestyle choices can reduce your risk.
Follow Life’s Simple 7 from the American Heart Association:
- Be active
- Keep a healthy weight
- Maintain a healthy blood pressure
- Maintain a healthy cholesterol
- Don't smoke or use smokeless tobacco
- Eat a heart-healthy diet
- Maintain a healthy blood glucose
And take two (2) Olivino every day! The Olive, Grape and Tomato antioxidants and polyphenols in Olivino may improve heart health by helping you maintain healthy levels of blood pressure, blood glucose and blood cholesterol.
Olivino may also help "relax" your blood vessels by improving the function of your endothelium—the single layer of cells that line and protect the inside of your blood vessels. A recent review of 14 clinical trials showed that consuming a Mediterranean Diet improves endothelial function—even in those with cardiovascular disease!
The Research Behind Olivino
Toi, P.L. et al. Preventative Role of Diet Interventions and Dietary Factors in Type 2 Diabetes Mellitus: An Umbrella Review. 2020. Nutrients Vol. 12:1-17.
Becerra-Tomás, N. et al. Mediterranean Diet, Cardiovascular Disease and Mortality in Diabetes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies and Randomized Clinical Trials 2020. Crit. Rev. Food. Sci. Nutr. Vol. 60, pp. 1207-1227.
Guasch-Ferré, M. et al. Dietary Polyphenols, Mediterranean Diet, Prediabetes, and Type 2 Diabetes: A Narrative Review of the Evidence. 2017. J. Oxid. Med. Cell Longev. Aug. 13:1-16.
Sleiman, D. et al. Effect of Mediterranean Diet in Diabetes Control and Cardiovascular Risk Modification: A Systematic Review. 2015. Front. Public Health Vol. 3:1-8.
Esposito, K. et al. A Journey into a Mediterranean Diet and Type 2 Diabetes: A Systematic Review with Meta-Analyses. 2015. BMJ Open. Vol. 5:1-10.
Georgoulis, M. et al. Mediterranean Diet and Diabetes: Prevention and Treatment. 2014. Nutrients Vol. 6:1406-1423.
Esposito, K. and Giugliano, D. Mediterranean Diet and Type 2 Diabetes. 2014. Diabetes Metab. Res. Rev. Vol. 30:34-40
Esposito, K. et al. Prevention and Control of Type 2 Diabetes by Mediterranean Diet: A Systematic Review. 2010. Diabetes Res. Clin. Pract. Vol. 89:97-102.
Saulle, R. et al. A Systematic Overview of the Scientific Literature on the Association Between Mediterranean Diet and the Stroke Prevention. 2019. Clin. Ter. Vol. 170:e396-408.
Psaltopoulou, T. et al. Mediterranean Diet, Stroke, Cognitive Impairment, and Depression: A Meta-Analysis. 2013. Ann. Neurol. Vol. 74:580-591.
Yubero-Serrano, E.M. et al. Mediterranean Diet and Endothelial Function in Patients with Coronary Heart Disease: An Analysis of the CORDIOPREV Randomized Controlled Trial. 2020. PLoS Med. Sept. 9:1-28.
Li, J. et al. The Mediterranean Diet, Plasma Metabolome, and Cardiovascular Disease Risk. 2020. Eur. Heart J. Vol. 41:2645-2656.
Rees K, et al. Mediterranean-Style Diet for the Primary and Secondary Prevention of Cardiovascular Disease: A Cochrane Review. 2020. Global Heart Vol. 15:1-29.
Temple, N.J. et al. The Mediterranean Diet and Cardiovascular Disease. Gaps in the Evidence and Research Challenges. 2019. Cardiol. Rev. Vol. 27:127-130.
Ditano-Vázquez, P. et al. The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil. 2019. Nutrients Vol. 11:1-28.
Rosato, V. et al. Mediterranean Diet and Cardiovascular Disease: A Systematic Review and Meta-Analysis of Observational Studies. 2019. Eur. J. Nutr. Vol. 58:173–191.
Martínez-González, M. et al. The Mediterranean Diet and Cardiovascular Health. A Critical Review. 2019. Circ. Res. Vol. 124:779–798.
Foscolou, F. et al. The Mediating Role of Mediterranean Diet on the Association Between Lp(a) Levels and Cardiovascular Disease Risk: A 10-year Follow-Up of the ATTICA Study. 2018. Clin. Biochem. Vol. 60:33-37.
Salas-Salvadó, J. et al. Mediterranean Diet and Cardiovascular Disease Prevention: What Do We Know? 2018. Prog. Cardiovasc. Dis. Vol. 61:62-67.
Mattioli A.V. et al. Mediterranean Diet Impact on Cardiovascular Diseases: A Narrative Review. 2017.
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Widmer, R.J. et al. The Mediterranean Diet, Its Components, and Cardiovascular Disease. 2015. Am. J. Med. Vol. 128:229–238.
Shen, J. et al. Mediterranean Dietary Patterns and Cardiovascular Health. 2015. Ann. Rev. Nutr. Vol. 35: 425-449.
Fonollá, J. et al. Effects of a Combination of Extracts from Olive Fruit and Almonds Skin on Oxidative and Inflammation Markers in Hypercholesterolemic Subjects: A Randomized Controlled Trial. 2020. J. Med. Food. Aug. 18:1-8.
Medina-Remón, A. et al. Polyphenol Intake from a Mediterranean Diet Decreases Inflammatory Biomarkers Related to Atherosclerosis: A Substudy of the PREDIMED Trial. 2017. Br. J. Clin. Pharmacol. Vol. 83:114-128.
Pais, P. et al. Impact of a Proprietary Standardized Olive Fruit Extract (SOFE) on Cardio-Ankle Vascular Index, Visual Analog Scale and C-Reactive Protein Assessments in Subjects with Arterial Stiffness Risk. 2016. Drugs R&D Vol. 16:355–368.
Campo, G. et al. Platelet Aggregation Values in Patients with Cardiovascular Risk Factors are Reduced by Verbascoside Treatment. A Randomized Study. 2015. Pharmacol. Res. Vol. 97:1-6.
Tresserra-Rimbau, A. et al. Intake of Total Polyphenols and Some Classes of Polyphenols Is Inversely Associated with Diabetes in Elderly People at High Cardiovascular Disease Risk. 2015. J. Nutr. Vol. 146:767-777.
Hernáez, Á. et al. Olive Oil Polyphenols Decrease LDL Concentrations and LDL Atherogenicity in Men in a Randomized Controlled Trial. 2015. J. Nutr. Vol. 145:1692-1697.
Covas, M.I. et al. The Effect of Polyphenols in Olive Oil on Heart Disease Risk Factors: A Randomized Trial. 2006. Ann. Intern. Med. Vol. 145: 333-341.
Hernáez Á. et al. Olive oil Polyphenols Enhance High-Density Lipoprotein Function in Humans: A Randomized Controlled Trial. 2014. Arterioscler. Thromb. Vasc. Biol. Vol. 34:2115-2119.
Schön, C. et al. Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers. 2021. Nutrients Vol. 13:1-18.
Odai, T. et al. Effects of Grape Seed Proanthocyanidin Extract on Vascular Endothelial Function in Participants with Prehypertension: A Randomized, Double-Blind, Placebo-Controlled Study. 2019. Nutrients Vol. 11:1-12.
Zhang, H. et al. The Impact of Grape Seed Extract Treatment on Blood Pressure Changes: A Meta-Analysis of 16 Randomized Controlled Trials. 2016. Medicine Vol. 95:1-7.
Park, E., et al. Effects of Grape Seed Extract Beverage on Blood Pressure and Metabolic Indices in Individuals with Pre-Hypertension: A Randomised, Double-Blinded, Two Arm, Parallel, Placebo-Controlled Trial. 2016. Br. J. Nutr. Vol. 115:226-238.
Li, S-H. et al. Effect of Grape Polyphenols on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials. 2015. PLoS One Vol. 10:1-12. NEW!
Ras, R.T., et al. Effect of Polyphenol-Rich Grape Seed Extract on Ambulatory Blood Pressure in Subjects with Pre- and Stage I Hypertension. 2013. Br. J. Nutr. Vol. 110:2234-2241.
Feringa, H.H.H., et al. The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials. 2011. J. Am. Diet. Assoc. Vol. 111:1173-1181.
Sivaprakasapillai, B. et al. Effect of Grape Seed Extract on Blood Pressure in Subjects with the Metabolic Syndrome. 2009. Metabolism Vol. 58:1743-1746.
Castaldo, L. et al. Red Wine Consumption and Cardiovascular Health. 2019. Molecules Vol. 24:1-20.
Breuss, J.M., et al. Resveratrol and Its Effects on the Vascular System. 2019. Int. J. Mol. Sci. Vol. 20:1-18.
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Wong, R.H.X. et al. Chronic Resveratrol Consumption Improves Brachial Flow-Mediated Dilatation in Healthy Obese Adults. 2013. J. Hypertens. Vol 31:1819-1827.
Wong, R.H.X. et al. Acute Resveratrol Supplementation Improves Flow-Mediated Dilatation in Overweight/Obese Individuals with Mildly Elevated Blood Pressure. 2011. Nutr. Metab. Cardiovasc. Dis. Vol. 21:851-866.
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Wolak, T. et al. Effect of Tomato Nutrient Complex on Blood Pressure: A Double Blind, Randomized Dose–Response Study. 2019. Nutrients Vol. 11:1-13.
Li, X. and Xu, J. Lycopene Supplement and Blood Pressure: An Updated Meta-Analysis of Intervention Trials. 2013. Nutrients Vol. 5: 3696–3712.
Nishimura, M. et al. Effect of 12-Week Daily Intake of the High-Lycopene Tomato (Solanum Lycopersicum), a Variety Named “PR-7”, on Lipid Metabolism: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study. 2019. Nutrients Vol. 11:1-13.
Cheng, H.M. et al. Tomato and Lycopene Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. 2017. Atherosclerosis Vol. 257:100-108.
Li, X. and Xu, J. Dietary and Circulating Lycopene and Stroke Risk: A Meta-Analysis of Prospective Studies. 2014. Sci. Reports Vol. 4: 1-7.
Gajendragadkar, P.R. et al. Effects of Oral Lycopene Supplementation on Vascular Function in Patients with Cardiovascular Disease and Healthy Volunteers: A Randomised Controlled Trial. 2014. PLOS ONE. Vol. 9:1-13.
Karppi, J. et al. Serum Lycopene Decreases the Risk of Stroke in Men. A Population-Based Follow-Study. 2012. Neurology Vol. 79:1540-1547.
Misra, R. et al. LycoRed as an Alternative to Hormone Replacement Therapy in Lowering Serum Lipids and Oxidative Stress Markers: A Randomized Controlled Clinical Trial. 2006. J. Obstet. Gynaecol. Res. Vol 32:299-304.
Health Benefits of Olivino Dietary Supplement
Research-based health benefits linked to consuming the traditional Mediterranean diet.
The health benefits of “The Fruits of the Mediterranean Diet” in a convenient capsule form.
Vegan | 100% Plant-based | Non-GMO | Gluten-free | Gelatin-free